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Difficulty identifying
odors could be an early sign of Alzheimer's
Researchers
have identified what could be an indicator of Alzheimer's disease that could be
an aid to a diagnosis in the early stages of the disease. That would lead to
non-invasive ways in monitoring the progression of the disease in patients.
What is this early sign that could be giving you a clear signal that you have
not taken into account? Read on and take note.
Difficulty identifying odors could be an early sign of
Alzheimer's
The
tests that doctors today carry out for diagnoses, are largely based on the
memory factor. This is a problem because when you start to show clear signs of
memory loss, this could have been going on for as long as 20 years.
Scientists
at McGill University in Quebec today are looking for a way to detect
Alzheimer's disease earlier, and for the first time have shown that loss of
smell could be an early sign of the disease.
In
a study that was published in Neurology, researchers did a study in 300 people
with potential risk of Alzheimer's per family member with the same disease.
Through routine and multiple-choice smell tests, they were asked to identify
some odors ranging from gum or gum to gasoline.
Of
those volunteers, one hundred with an average age of 63 years, also allowed to
be regularly tested via lumbar puncture for proteins related to Alzheimer's
disease in the spinal fluid. Lumbar puncture tests are used to follow the
progress of Alzheimer's disease in patients.
Thus,
these tests found that the people who had the greatest difficulty in
identifying odors in the scratch-and-sniff tests were those with the most
biological indications of Alzheimer's disease.
Marie-Elyse
Lafaille-Magnan, author of the study, mentioned that it was the first time that
someone was clearly able to show that the lack or loss of the ability to
identify odors has a correlation with biological markers that are those that
indicate the progress of the illness.
He
also referred to the fact that, for more than 30 years, scientists have
dedicated themselves to investigating the connection between memory loss and
the difficulty that people may have in identifying different smells. According
to her, this makes sense since it is known that the olfactory bulb (which has
to do with the sense of smell) and the entorhinal cortex (which has to do with
memory and naming smells) are among the first brain structures that they are
first affected by Alzheimer's disease.
Smell test before other symptoms appear
So
the smell test is a great way to detect the disease before other more severe
symptoms appear, the researchers said, even to try to reduce them once they
start.
They
also mentioned that if the onset of symptoms can be delayed by just five years,
this could be able to reduce the severity and prevalence of these symptoms by
more than 50 percent.
The
research team says there is still more to be done to reach clearer conclusions
to see if the sense of smell in people with Alzheimer's diminishes as the
disease progresses. However, there is hope with the further study that it is a test
that could be used instead of more expensive and invasive procedures such as
lumbar punctures.
However,
the director of research cautioned against only using odor practices to
diagnose the disease because the problems that identify odors can be indicative
of other medical conditions besides Alzheimer's disease and therefore should
not replace the current evidence.
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